How to Use Sermorelin Acetate

How to Use — Step-by-Step (Subcutaneous, Nightly)

Preparation

• Wash Hands – Soap and water.

• Gather Supplies – Vial, alcohol swabs, insulin syringe, sharps container.

Site Prep

• Select Site – Abdomen, thigh, or upper arm (rotate sites).

• Clean Skin – Alcohol swab; let air-dry.

Draw Dose

• Inspect Vial – Clear, particle-free solution.

• Measure – Draw 0.15–0.25 ml (per your prescribed mcg target).

• De-air – Tap syringe; expel bubbles.

Inject

• Pinch Skin – Create a small fold.

• Insert – ~45° into subcutaneous tissue.

• Inject Slowly – Depress plunger; withdraw at same angle.

• Press – Light pressure with gauze; do not rub.

After

• Dispose Safely – Sharps container.

• Timing – Nightly dosing; many protocols prefer empty stomach (2–3 hrs after last meal).

Possible Side Effects

Possible Side Effects

Common (usually mild/transient)

• Injection-site redness/itching, mild bruising

• Headache, warmth/flushing, transient fatigue

• Vivid dreams or sleep changes

Less Common / Monitor

• Mild water retention, joint stiffness, hand/foot tingling (carpal-tunnel–like)

• Lightheadedness, nausea

Serious (stop & seek care)

• Allergic reaction (hives, facial swelling, wheeze)

• Marked edema, chest symptoms, severe dizziness

Not exhaustive. If effects are severe, persistent, or unusual, discontinue and contact your clinician.

Additional Information

Additional Information

What is Sermorelin?
Sermorelin is a GHRH (1–29) analogue that supports endogenous growth hormone release in a physiologic, pulsatile manner.

How Does It Work?

• Amplitude Boost – Encourages pituitary GH pulses, especially overnight.

• Recovery & Composition – Often used to support sleep quality, recovery, and favorable body-composition trends under supervision.

Who Can Use It?
Adults under clinician care for GH-axis support. Not recommended during pregnancy/breastfeeding, for minors, or those with active malignancy. Use caution with uncontrolled hypertension, sleep apnea, or significant edema.

Clinical Supervision
Your clinician may monitor IGF-1, fasting glucose/insulin, lipids, BP, and sleep/energy metrics.

Shipping Information

Shipping & Cold Storage

• Refrigerate 2–8 °C (35–46 °F); do not freeze; protect from light.

• If pharmacy-reconstituted, follow the labeled beyond-use date (often up to 14 days refrigerated).

• Cold-chain shipping with ice packs; on arrival, refrigerate promptly and inspect for integrity/temperature breach.

Frequently Asked Questions